Cutaneous lesions are occasionally produced by systemic disorder so they may help in the diagnosis of the latter. On the other hand a cutaneous disease may affect the internal organs. Hence it should never be forgotten that skin is an organ of the whole body and should be considered as such, in the practice of dermatology.
Important e.g are:
Nutritional
Important e.g are:
Nutritional
- Pellagra, avitaminosis.
Metabolic
- Diabetes: Pruritus, moniliasis, furunculosis, carbuncle, xanthomatososis, necrobiosis lipoidica, tropic ulcers, gangrene.
- Amyloidosis cutis.
- Cirrohosis: Spider naevu, sallow complexion, paper money skin, pruritus.
- Prophyrinuria: Pigmentation, haydro aestivale
- Xanthomatosis
- Bronze diabetes or Henochromatosis
Endocrine
- Thyrotoxicosis: Pigmentation
- Myxedema: Alopecia, Myxedematous skin
- Cushing's syndrome: Flame shaped stria
- Piruitary cachexia (Simmonds): Alopecia
- Addisons disease: Pigmentation
- Menstrual disorder: Pigmentation, chloasma, alopecia. hirsuitism.
Focal Sepsis
(In teeth, ear, sinuses, tonsils, lung, gall bladder, kidneys, protrate etc)
- Pyenuc abscesses
- Lupus erythematous
- Bacteriodes
- Rosacea
- Discoid Eczema
- Acne vulgaris
- Urticaria
- Erythema multiforme
- Diermatits herpetiformis
- Dyshidrosis
Vascular disorder
- Raynaud's disease
- PAN
- Arteriosclerosis
- Buerger;s disease
Carcinomatosis
- Secondaris in skin
- Pigmentation
- Pruritus
- Acanthosis nigricans
Naevi
- Hemangioma of skin: Associated with angioma of brain
- Adenoma sebaceum Associated with tuberous sclerosus
- Neurofibromatosis: Associated with lessions in bones, nerves and eyes.
Collagen diseases
- Lupus erythematosus
- Scleroderma
- Dermatomyosiits
Fever and rashes
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